| β-Estradiol Basic information |
| Product Name: |
β-Estradiol |
| Synonyms: |
BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;β-Estradiol,99%(drywt.),ca3%water;1,3,5-Estratriene-3,17beta-diol;17beta-Estradiol;3,17beta-Dihydroxy-1,3,5(10)-estratriene;Dihydrofolliculin;Estradiol |
| CAS: |
50-28-2 |
| MF: |
C18H24O2 |
| MW: |
272.39 |
| EINECS: |
200-023-8 |
| Product Categories: |
Cell signaling and neurobiology; Sterols and steroids; Biochemical products; Lipids; Pharmaceutical raw materials; Other oxygen-containing compounds; Steroid hormones (hormones, glucocorticoids); Analyze standard samples; Pharmaceutical intermediates; Small molecule inhibitors; Natural products; Pharmaceutical and chemical industry; Steroids; estrogen; Pharmaceutical estrogen drugs; Intermediate of steroid hormone raw materials; Hormones; Estrogens; Biochemical reagents – other chemical reagents |
| Mol File: |
50-28-2.mol |
| Introduction |
Estradiol is a steroid hormone mainly secreted by ovarian follicles, corpus luteum, and placenta during pregnancy. It is the most important and biologically active hormone among estrogens. |
| Application |
Intermediate of estradiol valerate and estradiol benzoate. |
| β-Estradiol Chemical Properties |
| Melting point |
178-179 °C(lit.) |
| specific rotation |
D25 +76 to +83° (dioxane) |
| Boiling point |
355.44°C (rough estimate) |
| Density |
1.0708 (rough estimate) |
| refractive index |
80.4 ° (C=1, Dioxane) |
| flash point |
2℃ |
| Acidity coefficient (pKa) |
pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate) |
| Water solubility |
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils. |
| solubility |
Almost insoluble in water, soluble in acetone, slightly soluble in ethanol (96%), and slightly soluble in dichloromethane. |
| Storage |
room temp |
| form |
Powder |
| color |
White to off white |
