| KANAMYCIN Basic information | |
| Product Name: | KANAMYCIN |
| Synonyms: | o-6-deoxy-alpha-d-glucopyranosyl-(1.fwdarw.)]-2-deoxy-;y-alpha-d-glucopyranosyl-(1-4))-2-deoxy-;Kannamycin Monosulfate;KANAMYCIN BASE ENTERPRISE STANDARD;KanamycinMonosulfateA;1-O-[(1R)-2α-Hydroxy-3β-(3-amino-3-deoxy-α-D-glucopyranosyloxy)-4α,6α-diaminocyclohexane-1β-yl]-6-amino-6-deoxy-α-D-glucopyranose;4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine;Amikacin Impurity 4（Amikacin EP Impurity D） |
| CAS: | 59-01-8 |
| MF: | C18H36N4O11 |
| MW: | 484.5200-411-7 |
| EINECS: | 200-411-7 |
| Product Categories: | Antibiotics; Aminoglycoside antibiotics; Food additives; Animal materials. |
| Mol File: | 59-01-8.mol |
| Introduction | Kanamycin is a protein biosynthesis inhibitor that binds to 30S ribosomes resulting in misinterpretation of the mRNA code.If the bacteria produce an enzyme that destroys kanamycin, they can become resistant strains.Kanamycin – resistant plasmids are often used in molecular cloning as selective or marker genes. |
| Application | Gram-negative bacteria such as escherichia coli, salmonella, pneumoniae, proteus, pasteurella has a strong antibacterial effect,on staphylococcus aureus, tuberculosis bacteria, mold is also effective. |
| KANAMYCIN Chemical Properties | |
| alpha | D24 +146° (0.1N H2SO4) |
| Boiling point | 581.13°C (rough estimate) |
| density | 1.4042 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | 2-8°C |
| pka | pKa 6.40/7.55/8.40/9.40(H2O) (Uncertain) |
| form | liquid |
| color | white |
| EPA Substance Registry System | D-Streptamine, O-3-amino-3-deoxy-.alpha.-D-glucopyranosyl-(1.fwdarw.6)-O-[6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1.fwdarw.4)]-2-deoxy- (59-01-8) |