| Kisspeptin-10 Basic information | |
| Product Name: | Kisspeptin-10 |
| Synonyms: | MALIGNANTMELANOMAMETASTASIS-SUPPRESSORKISS-1(112-121)(HUMAN);METASTIN(HUMAN,45-54);METASTIN(45-54);METASTIN(45-54)AMIDE,HUMAN;METASTIN(45-54),HUMAN;KISSPEPTIN-13(4-13)(HUMAN);KISS-1GENEPRODUCT(HUMAN,112-121AMIDE);TYR-ASN-TRP-ASN-SER-PHE-GLY-LEU-ARG-PHE-NH2 |
| CAS: | 374675-21-5 |
| MF: | C63H83N17O14 |
| MW: | 1302.44 |
| EINECS: | 675-121-5 |
| Product Categories: | Peptide intermediates; Drug peptides; Standard products; Drug peptides; Peptide Receptors |
| Mol File: | 374675-21-5.mol |
| Introduction | Kisspeptin-10 (KP Kisspeptin-10, human) is an effective vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human inhibits tumor metastasis through its receptor GPR54. The Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation through NFATc4 mediated BMP2 expression. |
| Application | Kisspeptin-10(KP-10)and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals.Kisspeptin-10 protein binds to GPR54.Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells. |
| Kisspeptin-10 Chemical Properties | |
| density | 1.46±0.1 g/cm3(Predicted) |
| pKa | 9.96±0.15(Predicted) |
| storage temp. | -20°C |
| solubility | DMF：15 mg/ml； DMSO：15 mg/ml； DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml |
| form | Crystalline solid |
| color | white to off-white |