| KY19382 Basic information | |
| Product Name: | KY19382 |
| Synonyms: | 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro- |
| CAS: | 2226664-93-1 |
| MF: | C17H11Cl2N3O2 |
| MW: | 360.19 |
| EINECS: | 206-696-4 |
| Product Categories: | / |
| Mol File: | 2226664-93-1.mol |
| Introduction | KY19382 is an effective and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50 values of 19 and 10nM, respectively. KY19382 activates Wnt/β-catenin signaling by inhibiting the CXXC5-DVL interaction and GSK3β activity. KY19382 can be used in the research of metabolic diseases induced by a high-fat diet (HFD). |
| KY19382 Chemical Properties | |
| density | 1.58±0.1 g/cm3(Predicted) |
| pKa | 8.80±0.20(Predicted) |
| form | Powder |
| color | Brown to reddish-brown |